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Meng Xiao, Zhou Jing, Zhao Cai-Ning, Gan Ren-You, Li Hua-Bin. Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review. FOODS. DOI: 10.3390/foods9030340. MAR 2020.
来源：FOODS
发布时间：2020-05-04
作者：甘人友（通讯作者）
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| 作者: Meng, X (Meng, Xiao); Zhou, J (Zhou, Jing); Zhao, CN (Zhao, Cai-Ning); Gan, RY (Gan, Ren-You); Li, HB (Li, Hua-Bin) | |||||||||
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| 影响因子 (2018 年): 3.011 | |||||||||
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| 摘要: Resveratrol is a bioactive compound in many foods. Since its anticancer activity was reported in 1997, its health benefits have been intensively investigated. Resveratrol has antioxidant, anti-inflammatory, immunomodulatory, glucose and lipid regulatory, neuroprotective, and cardiovascular protective effects, therefore, can protect against diverse chronic diseases, such as cardiovascular diseases (CVDs), cancer, liver diseases, obesity, diabetes, Alzheimer's disease, and Parkinson's disease. This review summarizes the main findings of resveratrol-related health benefits in recent epidemiological surveys, experimental studies, and clinical trials, highlighting its related molecular mechanisms. Resveratrol, therefore, has been regarded as a potent candidate for the development of nutraceuticals and pharmaceuticals to prevent and treat certain chronic diseases. | |||||||||
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| 语言: English | |||||||||
| 文献类型: Review | |||||||||
| 作者关键词: resveratrol; bioactivities; anticancer; anti-obesity; antidiabetes; molecular mechanisms | |||||||||
| KeyWords Plus: NF-KAPPA-B; FATTY LIVER-DISEASE; OXIDATIVE STRESS; INFLAMMASOME ACTIVATION; CARDIOVASCULAR-DISEASE; CALORIC RESTRICTION; TRANS-RESVERATROL; MURINE MODEL; OBESE MICE; RAT MODEL | |||||||||
| 地址: [Meng, Xiao; Li, Hua-Bin] Sun Yat Sen Univ, Sch Publ Hlth, Dept Nutr, Guangdong Prov Key Lab Food Nutr & Hlth, Guangzhou 510080, Peoples R China. [Zhou, Jing] Hainan Med Univ, Sch Publ Hlth, Haikou 571199, Hainan, Peoples R China. Univ Hong Kong, Li Ka Shing Fac Med, Dept Clin Oncol, Hong Kong 999077, Peoples R China. [Gan, Ren-You] Chinese Acad Agr Sci, Inst Urban Agr, Res Ctr Plants & Human Hlth, Chengdu 610213, Peoples R China. |
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| 通讯作者地址: Gan, RY (通讯作者)，Chinese Acad Agr Sci, Inst Urban Agr, Res Ctr Plants & Human Hlth, Chengdu 610213, Peoples R China. | |||||||||
| 电子邮件地址: mengx7@mail2.sysu.edu.cn; hy0208035@hainmc.edu.cn; zhaocn@hku.hk; ganrenyou@caas.cn; lihuabin@mail.sysu.edu.cn | |||||||||
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| Web of Science 类别: Food Science & Technology | |||||||||
| 研究方向: Food Science & Technology | |||||||||
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This research was funded by China Central Public-interest Scientific Institution Basal Research Fund (Grant No. Y2020XK05), the National Key R&D Program of China (Grant No. 2018YFC1604400), and the Key Project of Guangdong Provincial Science and Technology Program (Grant No. 2014B020205002). |
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