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Xu Xiao-Yu, Zheng Jie, Meng Jin-Ming, Gan Ren-You, Mao Qian-Qian, Shang Ao, Li Bang-Yan, Wei Xin-Lin, Li Hua-Bin. Effects of Food Processing on In Vivo Antioxidant and Hepatoprotective Properties of Green Tea Extracts. ANTIOXIDANTS. DEC 2019. DOI: 10.3390/antiox8120572
来源:ANTIOXIDANTS
发布时间:2020-02-05
作者:甘人友(通讯作者)
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作者: Xu, XY (Xu, Xiao-Yu); Zheng, J (Zheng, Jie); Meng, JM (Meng, Jin-Ming); Gan, RY (Gan, Ren-You); Mao, QQ (Mao, Qian-Qian); Shang, A (Shang, Ao); Li, BY (Li, Bang-Yan); Wei, XL (Wei, Xin-Lin); Li, HB (Li, Hua-Bin) | ||||||||||||
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影响因子 (2018 年): 4.520 | ||||||||||||
摘要: Food processing can affect the nutrition and safety of foods. A previous study showed that tannase and ultrasound treatment could significantly increase the antioxidant activities of green tea extracts according to in vitro evaluation methods. Since the results from in vitro and in vivo experiments may be inconsistent, the in vivo antioxidant activities of the extracts were studied using a mouse model of alcohol-induced acute liver injury in this study. Results showed that all the extracts decreased the levels of aspartate transaminase and alanine aminotransferase in serum, reduced the levels of malondialdehyde and triacylglycerol in the liver, and increased the levels of catalase and glutathione in the liver, which can alleviate hepatic oxidative injury. In addition, the differences between treated and original extracts were not significant in vivo. In some cases, the food processing can have a negative effect on in vivo antioxidant activities. That is, although tannase and ultrasound treatment can significantly increase the antioxidant activities of green tea extracts in vitro, it cannot improve the in vivo antioxidant activities, which indicates that some food processing might not always have positive effects on products for human benefits. | ||||||||||||
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语言: English | ||||||||||||
文献类型: Article | ||||||||||||
作者关键词: green tea extract; food processing; tannase; ultrasound; antioxidant activity; liver injury | ||||||||||||
KeyWords Plus: INDUCED LIVER-INJURY; NONALCOHOLIC FATTY LIVER; REACTIVE OXYGEN; OXIDATIVE STRESS; ULTRASOUND; ACTIVATION; MECHANISMS; CAPACITY; TANNASE; HEPATOTOXICITY | ||||||||||||
地址: [Xu, Xiao-Yu; Zheng, Jie; Meng, Jin-Ming; Mao, Qian-Qian; Shang, Ao; Li, Bang-Yan; Li, Hua-Bin] Sun Yat Sen Univ, Sch Publ Hlth, Dept Nutr, Guangdong Prov Key Lab Food Nutr & Hlth, Guangzhou 510080, Peoples R China. [Gan, Ren-You] Chinese Acad Agr Sci, Inst Urban Agr, Chengdu 610213, Peoples R China. [Gan, Ren-You; Wei, Xin-Lin] Shanghai Jiao Tong Univ, Sch Agr & Biol, Dept Food Sci & Technol, Shanghai 200240, Peoples R China. |
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通讯作者地址: Li, HB (通讯作者),Sun Yat Sen Univ, Sch Publ Hlth, Dept Nutr, Guangdong Prov Key Lab Food Nutr & Hlth, Guangzhou 510080, Peoples R China. Gan, RY (通讯作者),Chinese Acad Agr Sci, Inst Urban Agr, Chengdu 610213, Peoples R China. Gan, RY (通讯作者),Shanghai Jiao Tong Univ, Sch Agr & Biol, Dept Food Sci & Technol, Shanghai 200240, Peoples R China. |
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电子邮件地址: xuxy53@mail2.sysu.edu.cn; zhengj37@mail2.sysu.edu.cn; mengjm@mail2.sysu.edu.cn; ganrenyou@caas.cn; maoqq@mail2.sysu.edu.cn; shangao@mail2.sysu.edu.cn; liby35@mail2.sysu.edu.cn; weixinlin@sjtu.edu.cn; lihuabin@mail.sysu.edu.cn | ||||||||||||
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Web of Science 类别: Biochemistry & Molecular Biology; Chemistry, Medicinal; Food Science & Technology | ||||||||||||
研究方向: Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Food Science & Technology | ||||||||||||
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This study was supported by the National Key R&D Program of China (No. 2018YFC1604405), the Fundamental Research Funds for the Central Universities (No. 19ykyjs24), the Agri-X Interdisciplinary Fund of Shanghai Jiao Tong University (No. Agri-X2017004), Shanghai Basic and Key Program (No. 18JC1410800), and the Key Project of Guangdong Provincial Science and Technology Program (No. 2014B020205002). |
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